Posts Tagged cells
Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells
Product Description
This digital document is a journal article from DNA Repair, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
Oligonucleotides (ODNs) can direct the exchange of single nucleotides at specific sites in the mammalian genome. It is generally believed that the ODN aligns in homologous register w… More >>
Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells
Tags: activates, amazon, cells, Chk1, Chk2, corrected, digital document, dna repair, elsevier, Gene, gene repair, journal article, mammalian genome, media library, nucleotides, repair, replication, stalls, TargetedRelated posts
Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks
Product Description
This digital document is a journal article from DNA Repair, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
The repair of point mutations directed by modified single-stranded DNA oligonucleotides is dependent on the activity of proteins involved in homologous recombination (HR). As a conse… More >>
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Nonviral Vectors for Gene Therapy
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Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of “healthy genes” into patients’ cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflamatory activity and negative immunological responses to the genes. Viral vectors were also unable to meet the needs of the pharmaceutical community: they were not reproducib… More >>
Nonviral Vectors for Gene Therapy
Tags: 10 years, cells, Gene, gene therapy, genes, immunological responses, Nonviral, nonviral vectors, obstacle, pharmaceutical community, Therapy, Vectors, viral vectorsRelated posts