Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells


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This digital document is a journal article from DNA Repair, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Oligonucleotides (ODNs) can direct the exchange of single nucleotides at specific sites in the mammalian genome. It is generally believed that the ODN aligns in homologous register w… More >>

Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells

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